Metabolic disorders

FlorInScan

Laboratoires Réunis has many years of experience in the field of intestinal health and stool analysis. For nearly 17 years, we have been offering the FlorInScan extensive stool analysis. The individual profiles are continuously developed and adapted according to the latest scientific findings.

The following FlorInScan and other profiles are available at Laboratoires Réunis for targeted diagnostics and prevention:

FlorInScan includes the classical, quantitative, culture-based determination of fecal microflora (aerobic and anaerobic flora, fungi and yeasts), as well as the analysis of digestive performance by determining food residues,  the pH value and pancreatic elastase. An examination for occult blood in stool is also included. FlorInScan is an important component of preventive and personalized medicine for unclear gastrointestinal complaints or diseases of allergic or immunological origin.

FlorInScan Plus is an advanced screening: in addition to the determination of fecal microflora status, digestive performance and blood in stool, immunological and inflammatory markers (secretory IgA, calprotectin and alpha-1-antitrypsin) are included. These markers allow conclusions on invasive mucosal changes and permeability disorders, e.g. in the context of allergies and chronic inflammatory processes or tumors.

FlorInScan microbiome profile is our newly developed extensive profile based on molecular microbiome analysis. It includes the determination and quantification of health-related, anaerobic bacteria, which can only be detected by molecular genetic methods.

The FlorInScan microbiome profile ideally complements the classic, cultural-based FlorInScan analysis. The analysis of these relevant bacterial groups can additionally be included in the medical interpretation and prevention of chronic inflammatory bowel disease (IBD), irritable bowel syndrome, colon cancer and diabetes as well as in further therapy.

The vaginal flora is a complex ecosystem dominated mainly by lactobacilli sp.. In addition, a large variety of anaerobic, aerobic bacteria and Candida sp. occur as a transient accompanying flora with a low numbers of germs.

By producing lactic acid, lactobacilli keep the vaginal ecosystem in a slightly acidic pH range (3.8-4.5); additional antimicrobial substances such as H₂O₂ or bacteriocins keep the vaginal environment in a dynamic but sensitive balance.

A disturbed vaginal flora or a bacterial vaginosis, as well as recurrent infections carry an increased risk of ascending infections and are associated with the onset of prematurity and pregnancy complications. In addition, yeast colonization of the birth path is a common cause of 'diaper dermatitis' and 'oral thrush' in newborns. Women with recurrent vaginal complaints, vaginitis or repeated urinary tract infections should therefore be tested.

With FlorVaScan, Laboratoires Réunis offers you a comprehensive, multi-component analysis profile for the examination of the vaginal microflora. The following examinations are included in the test profile:

• Quantification et identification microbiologique des levures et des lactobacilles (analyse par PCR et culture)
• Microscopic examination of the vaginal exudate according to standardized criteria (Nugent Score) and determination of the degree of purity
• Quantitative analysis of H₂O₂-producing lactobacilli
• Quantitative analysis of the anaerobic and aerobic accompanying flora
• Molecular biological detection of Trichomonas spp. and Gardnerella vaginalis, as well as the main causative agent of bacterial vaginosis
  (Atopobium vaginae, Mobiluncus spp.)
• Quantification and microbiological identification of yeasts and lactobacilli (PCR analysis and culture)

FlorVaScan allows the doctor a targeted and therefore effective therapy. Through a detailed overall assessment of the vaginal flora, he can counteract an imbalance at an early stage and prevent the circulation of recurrent infections via specifying treatment recommendations.

Laboratoires Réunis offers in addition to its profiles additional examination methods:

• Urinary oestrogen metabolites
• Lactobacilli

Vitamins are crucial parts of biochemical conversions in the body, such as co-factors in enzyme reactions and play an important role against oxidative stress. Deficiency or excess of vitamins can lead to a decreased function of several (organ) systems and the human body as a whole. Therefore, vitamin testing gives insight into absolute and relative deficiencies, and provides information about the impact of dietary changes and supplementations.

Laboratoires Réunis offers the following tests related to vitamins:

• Vitamin B3
• folic acid (vitamin B9)
• Vitamin B12
• Holotranscobalamin (active vitamin B12)
• Biotin (vitamin H)

Minerals are dissolved substances that are present within and outside the body cell. They are essential for several metabolic processes like enzyme activation, regulation of water balance and pH. Increased or decreased levels can impair metabolic processes and additionally give information about possible diseases.

Laboratoires Réunis offers complete analysis of minerals including sodium, potassium, magnesium, copper, iron, zinc, selenium. Single analysis on demand.

Short-chain fatty acids are formed in the intestine during the metabolism of fibers and complex carbohydrates by bacteria. The fatty acids acetate, propionate and butyrate are particularly important: they are the main source of energy for the intestinal epithelium, stimulate the formation of mucus, have anti-inflammatory effects (mainly butyrate) and counteract weigh increase (mainly propionate).

A balanced ratio of short-chain fatty acids is thus essential for intestinal health. With the help of the profile for short-chain fatty acids, targeted nutritional measures as well as combinations with special probiotics can be taken.