Women's health

FlorInScan

A balanced intestinal flora is essential for optimal health

FlorInScan

Laboratoires Réunis has many years of experience in the field of intestinal health and stool analysis. For nearly 17 years, we have been offering the FlorInScan extensive stool analysis. The individual profiles are continuously developed and adapted according to the latest scientific findings.

The following FlorInScan and other profiles are available at Laboratoires Réunis for targeted diagnostics and prevention:

FlorInScan includes the classical, quantitative, culture-based determination of fecal microflora (aerobic and anaerobic flora, fungi and yeasts), as well as the analysis of digestive performance by determining food residues,  the pH value and pancreatic elastase. An examination for occult blood in stool is also included. FlorInScan is an important component of preventive and personalized medicine for unclear gastrointestinal complaints or diseases of allergic or immunological origin.

FlorInScan Plus is an advanced screening: in addition to the determination of fecal microflora status, digestive performance and blood in stool, immunological and inflammatory markers (secretory IgA, calprotectin and alpha-1-antitrypsin) are included. These markers allow conclusions on invasive mucosal changes and permeability disorders, e.g. in the context of allergies and chronic inflammatory processes or tumors.

FlorInScan microbiome profile is our newly developed extensive profile based on molecular microbiome analysis. It includes the determination and quantification of health-related, anaerobic bacteria, which can only be detected by molecular genetic methods.

The FlorInScan microbiome profile ideally complements the classic, cultural-based FlorInScan analysis. The analysis of these relevant bacterial groups can additionally be included in the medical interpretation and prevention of chronic inflammatory bowel disease (IBD), irritable bowel syndrome, colon cancer and diabetes as well as in further therapy.

SKINgen

Special preventive genetic profile dedicated to skin aging

Preventive genetic profile dedicated to skin aging

Processes and pathways such as detoxification, inflammation, oxidative stress and epidermal integrity are analyzed and individualized recommendations are provided.
SKINgen helps you protect and improve your skin health capacities.

This test is carried out on a sub-contracted basis by an accredited laboratory.

FlorVaScan

A multi-component analysis profile for the examination of the vaginal microflora

The vaginal flora is a complex ecosystem dominated mainly by lactobacilli sp.. In addition, a large variety of anaerobic, aerobic bacteria and Candida sp. occur as a transient accompanying flora with a low numbers of germs.

By producing lactic acid, lactobacilli keep the vaginal ecosystem in a slightly acidic pH range (3.8-4.5); additional antimicrobial substances such as H2O2 or bacteriocins keep the vaginal environment in a dynamic but sensitive balance.

A disturbed vaginal flora or a bacterial vaginosis, as well as recurrent infections carry an increased risk of ascending infections and are associated with the onset of prematurity and pregnancy complications. In addition, yeast colonization of the birth path is a common cause of 'diaper dermatitis' and 'oral thrush' in newborns. Women with recurrent vaginal complaints, vaginitis or repeated urinary tract infections should therefore be tested.

With FlorVaScan, Laboratoires Réunis offers you a comprehensive, multi-component analysis profile for the examination of the vaginal microflora. The following examinations are included in the test profile:

  • Quantification et identification microbiologique des levures et des lactobacilles (analyse par PCR et culture)
  • Microscopic examination of the vaginal exudate according to standardized criteria (Nugent Score) and determination of the degree of purity
  • Quantitative analysis of H2O2-producing lactobacilli
  • Quantitative analysis of the anaerobic and aerobic accompanying flora
  • Molecular biological detection of Trichomonas spp. and Gardnerella vaginalis, as well as the main causative agent of bacterial vaginosis
    (Atopobium vaginae, Mobiluncus spp.)
  • Quantification and microbiological identification of yeasts and lactobacilli (PCR analysis and culture)

FlorVaScan allows the doctor a targeted and therefore effective therapy. Through a detailed overall assessment of the vaginal flora, he can counteract an imbalance at an early stage and prevent the circulation of recurrent infections via specifying treatment recommendations.

OPTIMETgen

Methylation and detoxification efficiencies

OPTIMETgen is a panel of SNPs related to methylation and detoxification efficiencies. Based on the results, personalized recommendations are provided to optimize metabolic cycles of the methyl groups. These recommendations are also beneficial in the prevention of age-related diseases and aging.

This test is carried out on a sub-contracted basis by an accredited laboratory.

WEIGHTgen

Preventive genetic profile dedicated to weight control

Preventive genetic profile dedicated to weight control

Metabolic pathways and physiological parameters analyzed in this panel are related to adipogenesis, anthropometry, appetite control, energy expenditure, lipid metabolism and inflammation.

Personalized recommendations of WEIGHTgen can help manage and optimize weight conditions.

This test is carried out on a sub-contracted basis by an accredited laboratory.

FEMgen

Preventive genetic test to lessen the HRT side effects

Preventive genetic test to counteract side effects of hormone replacement therapy

The test analyzes polymorphisms involved in the metabolism of estrogens and detoxification of estrogen metabolites. FEMgen may be performed by women prior to hormonal replacement therapy or by women who have a family history of breast cancer.

This test is carried out on a sub-contracted basis by an accredited laboratory.

EMOgen

Preventive genetic test against emotional instability

Preventive genetic test against emotional instability

EMOgen analyzes polymorphisms in relation with the metabolism of neurotransmitters (dopamine, serotonin), the homocysteine metabolism, serotonin synthesis and transport. This test allows to counteract the development of depression and anxiety disorders.

This test is carried out on a sub-contracted basis by an accredited laboratory.

DIABETOgen

Preventive genetic test against type II diabetes

Preventive genetic test against type II diabetes

The test analyzes polymorphisms involved in mechanisms linked to type II diabetes such as insulin and leptin sensitivity and other risk factors such as overweight.

DIABETOgen is indicated in case of family history of type II diabetes and/or metabolic syndrome.

This test is carried out on a sub-contracted basis by an accredited laboratory.

BASICgen

Overview of genetic health capacities

Preventive genetic basic test

This test allows a first overview of genetic health capacities such as lipid, carbohydrate and homocysteine and lactose metabolism, lactose intolerance, needs in vitamins, immune defense as well as detoxification markers.

This test is carried out on a sub-contracted basis by an accredited laboratory.

Well-being

Detoxification capacities, cardiovascular diseases, skin and dental health, weight, bone health, physical and mental fitness

Complete preventive genetic profile entirely dedicated to anti-aging

The Well-being profile covers detoxification capacities, cardiovascular diseases, skin and dental health, weight management, bone health, physical and mental fitness. The results provide personalized and detailed recommendations on nutrition, diet, micronutrition and lifestyle.

The Well-being profile is meant for health-conscious individuals who want to maintain their health conditions by taking appropriate measures for a better aging.

This test is carried out on a sub-contracted basis by an accredited  laboratory.

ALOPECIAgen

Androgen receptor and three other polymorphisms involved in androgenetic alopecia

Preventive genetic test against androgenetic alopecia

ALOPECIAgen targets the androgen receptor and three other polymorphisms involved in the development of androgenetic alopecia. The ALOPECIAgen profile analyzes and allows to distinguish between three different risk groups before the occurrence of any symptoms.

Depending on the risk and the gender, a treatment with minoxidil and/or finasteride may be recommended. Other nutrigenetic and lifestyle recommendations given in the profile may contribute to the prevention of androgenetic alopecia.

This test is carried out on a sub-contracted basis by an accredited laboratory.

THROMBOgen

Preventive genetic test against deep vein thrombosis

Preventive genetic test against deep vein thrombosis

The test analyzes polymorphisms involved in hemostasis, thrombus formation and in the folate metabolism. The information obtained with the profile allows early action in order to decrease the relative risk of thrombosis. THROMBOgen is indicated in case of family history of thrombosis, prior to oral contraception, in case of repetitive spontaneous abortions and atherosclerosis in young people.

This test is carried out on a sub-contracted basis by an accredited laboratory.

CARDIOgen

Preventive genetic test against cardiovascular diseases

Preventive genetic test against cardiovascular diseases

The test analyzes polymorphisms involved in oxidative stress, hypertension, homocysteine, lipid metabolism disorders and thrombosis.

CARDIOgen can be carried out in case of a family history of cardiovascular diseases, suspicion of cardiovascular diseases, lipid and homocysteine metabolism disorders and arterial hypertension.

This test is carried out on a sub-contracted basis by an accredited laboratory.

COLOgen

Preventive genetic test against sporadic colorectal carcinoma

Preventive genetic test against sporadic colorectal carcinoma

Genetic polymorphisms analyzed in COLOgen target a pathway involved in cell growth, proliferation, differentiation and apoptosis. COLOgen should be prescribed to individuals with a family history of colorectal cancer or of intestinal polyps.

This test is carried out on a sub-contracted basis by an accredited laboratory.

OSTEOgen

Preventive genetic test against osteoporosis

Preventive genetic test against osteoporosis

Analyzed polymorphisms play a role in the synthesis of collagen, absorption and utilization of calcium by the bone, osteoclast activity, and lactase deficiency.

OSTEOgen is recommended to young individuals aiming to strengthen the bone mass as early as possible in order to slow down or prevent the development of osteoporosis.

This test is carried out on a sub-contracted basis by an accredited laboratory.

Profile short chain fatty acids

A balanced ratio of short-chain fatty acids is essential for intestinal health

Short-chain fatty acids are formed in the intestine during the metabolism of fibers and complex carbohydrates by bacteria. The fatty acids acetate, propionate and butyrate are particularly important: they are the main source of energy for the intestinal epithelium, stimulate the formation of mucus, have anti-inflammatory effects (mainly butyrate) and counteract weigh increase (mainly propionate).

A balanced ratio of short-chain fatty acids is thus essential for intestinal health. With the help of the profile for short-chain fatty acids, targeted nutritional measures as well as combinations with special probiotics can be taken.

BACTOdent Plus

Analysis of seven marker pathogens for periodontitis

Marker bacteria for periodontitis

Periodontitis and peri-implantitis are caused by periodontal bacteria and are generally preceded by gingivitis.
BACTOdent Plus is a highly specific profile to effectively determine 7 relevant marker pathogens for periodontitis.

This test is carried out on a sub-contracted basis by an accredited laboratory.

Histamine Intolerance

Various targeted analyses to detect histamine intolerance

Laboratoires Réunis offers various  targeted examination methods for the detection of histamine intolerance:

  • Determination of DAO activity in serum
  • Determination of histamine concentration in stool
  • HISTAMINgen: genetic study of the DAO gene. This test determines if there is a genetic predisposition to histamine intolerance.
ImuPro

IgG food allergy testing and nutritional guidance

The ImuPro Concept - Diagnostics and unique post-test guidance

With an IgG food allergy (also called type III food allergy), the immune system reacts to usually harmless food allergens and produces specific antibodies, called IgG antibodies. These antibodies can then cause inflammatory reactions which may lead to various chronic complaints; the symptoms appear delayed up to three days after the consumption of a trigger food.

How does an IgG food allergy develop? Due to medicines, infections, mycosis, stress and environmental poisons, the integrity of the intestinal wall can be damaged and food components can slip between the intestinal cells. In some cases this triggers an immune response and the immune system starts to produce specific IgG antibodies against them.

ImuPro is a concept that combines a sophisticated and reliable blood analysis for IgG food allergies with unique post-test guidance. In an extensive laboratory analysis, high levels of IgG antibodies specific to particular food proteins are identified. The lab provides the doctor and patient with the test results and personal nutritional guidelines.

ImuPro is recommended in case of:

Bloating, constipation, irritable bowel syndrome (IBS), headache, migraine, obesity, depression, skin and joint problems.

ImuPro options:

· ImuPro Screen provides an individual analysis of 22 foods. It is a simple way to find out quickly whether an IgG food allergy might exist. It is a purely diagnostic examination and does not include any dietary recommendations.

· ImuPro Basic tests the 90 most important foods, such as typical kinds of meat, vegetables, fruits, cereals, dairy products and chicken egg. As well as a comprehensive report with accurate results at a glance, the documents will contain personal nutritional guidelines including individual recommendations.

· ImuPro Basic+ analyzes 180 foods. In addition to the typical most common vegetables, meat, fruits, cereals, dairy products and eggs, their alternatives and region-specific foods are also tested. The patients receives a comprehensive report with accurate results at the glance, nutritional guidelines including individual recommendations and a recipe book.

· ImuPro Complete tests 270 foods and additives (incl. the 90 foods in ImuPro Basic). In addition to the typical kinds of meat, vegetables, fruits, cereals, milk and egg, their alternatives and region-specific foods are also tested. Furthermore, a huge number of spices, tea, coffee, wine and also thickening agents and preservatives are examined. You will receive a comprehensive report with accurate results at a glance and personal nutritional guidelines which lead you through your change in diet. Your results pack also includes individual recommendations and a recipe book which is specifically tailored to your personal needs.

MethylAge

Test if your lifestyle affects your metabolism

Actual Biological Age estimation 

  

Feeling old too soon? Test if your Lifestyle affects your metabolism. 

Epigenetics is a mechanism that allows to adapt gene expression to environmental factors. Your birthday gives a chronological age, some epigenetic biomarkers may give another biological one. This test will help change or reinforce good habits for a younger biological age. 

MTHFR methylentetrahydrofolate reductase

Increased homocysteine levels can increase the risk of thrombosis and atherosclerosis

Homocysteinemia

A thermolabile variant of the methylenetetrahydrofolate reductase, caused by a mutation at position 677, is associated with an increased homocysteine level. An increased homocysteine level can increase the risk of developing thrombosis and atherosclerosis.

This test is carried out on a sub-contracted basis by an accredited laboratory.

NICOTINEgen (nicotine addiction)

Preventive genetic test against nicotine addiction

Preventive genetic test against nicotine addiction

The NICOTINEgen profile characterizes genetic variations in the nicotinic acetylcholine receptor associated with nicotine addiction. Results allow to define the risk of addiction and to facilitate the choice between a nicotine replacement therapy (patches or chewing-gum containing nicotine) or a medical therapy (e.g. bupropion or varenicline).

This test is carried out on a sub-contracted basis by an accredited  laboratory.

Lyme borreliosis

Lyme borreliosis is the most common bacterial disease in Europe transmitted by ticks. Depending on the region 5-35% of the ticks are infected. The clinical manifestations are multi-faceted; especially the chronic form with inflammation of the nervous system, the heart muscle and the joints is a therapeutic challenge. Efficient diagnostic tests are therefore essential for appropriate treatment measures.

The following tests are available at Laboratoires Réunis for targeted diagnostics and prevention:

  • Serology
  • ELIspot
  • Borrelia detection in ticks (PCR)
  • LTT (only available in Luxembourg)
Oxidative stress

Imbalance between antioxidants and free radicals

Oxidative stress

Oxygen is vital because it allows the production of energy from organic matter. Paradoxically, oxygen can also be harmful: physiological processes such as cellular respiration or protective mechanisms of the body constantly produce highly reactive oxygen compounds, including free radicals, all highly toxic.

Oxidative stress is defined as a disturbance in the balance between the production of free radicals and the ability of the body to neutralize them leading to an accumulation of free radicals. Oxidative stress over a long period may promote the development of diseases: cardiovascular diseases, chronic infectious diseases, inflammatory and neurodegenerative diseases and even cancer. Besides, oxidative stress plays also an important role in aging.

The factors or conditions below may contribute to oxidative stress:

  • Heavy physical efforts
  • Unbalanced diet
  • Consumption of tobacco and alcohol
  • Chronic fatigue
  • Physical or mental stress
  • Chronic and inflammatory diseases
  • Treatments such as chemotherapy, radiotherapy, oral contraception
  • Pollution, UV radiation
  • Infections

There is a conclusive link between high levels of oxidative stress and a patient’s health.
However, in more than 80% of cases, it is possible to reduce oxidative stress and thus to improve health status, regardless of clinical context or patient’s age.

Targeted laboratory diagnoses are therefore essential for an early diagnosis and treatment of oxidative stress.

Laboratoires Réunis offers, in addition to a wide range of individual analyses, the following laboratory diagnostic profiles for the detection of oxidative stress:

  • Oxidative stress-base profile: antioxidative capacity, oxidized LDL and 8-OHdG
  • Profile of complete oxidative stress: antioxidant capacity, 8-OHdG, oxidized LDL, SOD, GPX, Se, Zn, Vit A & E, ubiquinone, citrulline, nitrotyrosine,
  • Nitrosative stress profile: ubiquinone, nitrotyrosine, nitrophenylacetic acid, citrulline
freeVitaminDgen

Genetic test to determine the bioavailability of free vitamin D

Genetic test to determine the bioavailability of free vitamin D

Vitamin D regulates several biological functions but up to 90% of vitamin D is bound to the vitamin D binding protein (VDBP) being responsible  for its transportation.
Less than 1% of the vitamin D only is freely available and therefore biologically active.
By investigating SNPs within the VDBP gene, which are associated with a different affinity to vitamin D metabolites, freeVitaminDgen detects if there is a deficiency of bioavailable vitamin D.

This test is carried out on a sub-contracted basis by an accredited laboratory.

Vitamins

To diagnose vitamin deficiencies

Vitamins are crucial parts of biochemical conversions in the body, such as co-factors in enzyme reactions and play an important role against oxidative stress. Deficiency or excess of vitamins can lead to a decreased function of several (organ) systems and the human body as a whole. Therefore, vitamin testing gives insight into absolute and relative deficiencies, and provides information about the impact of dietary changes and supplementations.

Laboratoires Réunis offers the following tests related to vitamins:

  • Vitamin B3
  • folic acid (vitamin B9)
  • Vitamin B12
  • Holotranscobalamin (active vitamin B12)
  • freeVitaminDgen (genetic test to determine the bio-availability of free vitamin D)
  • Biotin (vitamin H)
Minerals

To detect deficiencies across the mineral spectrum

Minerals are dissolved substances that are present within and outside the body cell. They are essential for several metabolic processes like enzyme activation, regulation of water balance and pH. Increased or decreased levels can impair metabolic processes and additionally give information about possible diseases.

Laboratoires Réunis offers complete analysis of minerals including sodium, potassium, magnesium, copper, iron, zinc, selenium. Single analysis on demand.