Histamine intolerance (HIT) is an imbalance in the histamine metabolism characterized by an increased supply of ingested or released histamine and an insufficient capacity of histamine degradation. HISTAMINgen analyzes the genetic predisposition for HIT.
In combination with the measurement of the activity of the histamine degrading enzyme diaminoxidase (DAO) and the evaluation of histamine levels, the results allow the differentiation between a primary and secondary histamine intolerance.
HISTAMINgen additionally evaluates the genetic penetrance for a reduced DAO-activity (HITscore).
This test is carried out on a sub-contracted basis by an accredited laboratory.