Paediatrics
LACTOgen
Primary lactose intolerance
Primary lactose intolerance
Lactose intolerance is caused by a lactase deficiency in the small bowel. Lactose cannot be hydrolyzed enzymatically into galactose and glucose and reaches the colon undigested. In the colon lactose binds water and provokes fermentation. These fermentation processes and the osmotic activity of undigested lactose cause the typical gastrointestinal symptoms.
With LACTOgen the genetic predisposition for a primary lactose intolerance is evaluated.
This test is carried out on a sub-contracted basis by an accredited laboratory.
Gilbert‘s syndrome
Mild liver disorder linked to elevated levels of bilirubin
Gilbert‘s syndrome is a relative mild condition characterized by periods of elevated levels of bilirubin (hyperbilirubinemia). It is caused by changes in the UGT gene which are examined in this profile.
This test is carried out on a sub-contracted basis by an accredited laboratory.
Crohn‘s disease
Susceptibility for Crohn's disease
Susceptibility for Crohn‘s disease
Several genes are associated with inflammatory bowel disease (IBD) susceptibility; most of them encode for proteins that regulate microbiota (NOD2) or that may control host response (IL-23R). A patient with NOD2 homozygosity carries a 20-fold increased risk for CD. In this profile SNPs in NOD2 and IL-23R genes are determined.
This test is carried out on a sub-contracted basis by an accredited laboratory.
WEIGHTgen
Preventive genetic profile dedicated to weight control
Preventive genetic profile dedicated to weight control
Metabolic pathways and physiological parameters analyzed in this panel are related to adipogenesis, anthropometry, appetite control, energy expenditure, lipid metabolism and inflammation.
Personalized recommendations of WEIGHTgen can help manage and optimize weight conditions.
This test is carried out on a sub-contracted basis by an accredited laboratory.
COELIAgen
Determination of the disease predisposition allele
Celiac disease
Also known as gluten-sensitive enteropathy, is an inflammatory autoimmune disorder in genetically predisposed patients (HLA-DQ2/DQ8 positive) that mainly affects the small intestine. With COELIAgen the celiac disease predisposition allele can be determined.
This test is carried out on a sub-contracted basis by an accredited laboratory.
Fructose Intolerance
Test for the detection of intestinal fructose intolerance
For the detection of intestinal fructose intolerance, Laboratoires Réunis offers the following analysis: Bacterial cleavage activity of fructose (as well as sorbitol) in stool.
For the detection of hereditary fructose intolerance, Laboratoires Réunis tests the most common mutations in the aldolase B gene with detailed interpretation of the results. Please ask for our genetic profile of hereditary fructose intolerance.
For further information please contact: sales@labo.lu oder +352 780 290-1
MTHFR methylentetrahydrofolate reductase
Increased homocysteine levels can increase the risk of thrombosis and atherosclerosis
Homocysteinemia
A thermolabile variant of the methylenetetrahydrofolate reductase, caused by a mutation at position 677, is associated with an increased homocysteine level. An increased homocysteine level can increase the risk of developing thrombosis and atherosclerosis.
This test is carried out on a sub-contracted basis by an accredited laboratory.